{"id":51077,"date":"2026-07-20T17:10:20","date_gmt":"2026-07-20T15:10:20","guid":{"rendered":"https:\/\/vibefarma.com\/us\/science\/"},"modified":"2026-08-14T04:40:34","modified_gmt":"2026-08-14T08:40:34","slug":"science","status":"publish","type":"page","link":"https:\/\/vibefarma.com\/us\/science\/","title":{"rendered":"Science"},"content":{"rendered":"<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Bricolage+Grotesque:opsz,wght@12..96,400..700&family=Inter+Tight:wght@400;500;600;700&family=JetBrains+Mono:wght@400;500&display=swap'); .vf-sci{--teal:#004B53;--teal2:#00636d;--green:#258055;--lime:#D1FF80;--mint:#9DE0DE; --beige:#F4F2DC;--offwhite:#F8FDFF;--grey:#2A2A2A;--soft:#40625f; font-family:'Inter Tight',sans-serif;color:var(--grey);line-height:1.62;background:#fff;} .vf-sci *{box-sizing:border-box;margin:0;padding:0;} .vf-sci .wrap{max-width:1080px;margin:0 auto;padding:0 24px;} .vf-sci .eyebrow{font-family:'JetBrains Mono',monospace;text-transform:uppercase; letter-spacing:.14em;font-size:.72rem;color:var(--green);margin-bottom:16px;} .vf-sci .step-tag{font-family:'JetBrains Mono',monospace;text-transform:uppercase; 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color:var(--green);text-transform:uppercase;margin-bottom:12px;} .vf-sci .pillar .val{font-family:'Bricolage Grotesque',sans-serif;font-weight:700;font-size:2.1rem; color:var(--teal);line-height:1;margin-bottom:8px;} .vf-sci .spm-note{background:var(--offwhite);border:1px solid #bfe0cf;border-left:4px solid var(--green); border-radius:12px;padding:22px 26px;margin-top:24px;text-align:left;} .vf-sci .spm-note strong{color:var(--teal);} .vf-sci .badges{display:flex;gap:12px;justify-content:center;flex-wrap:wrap;margin-top:30px;} .vf-sci .badge{font-family:'JetBrains Mono',monospace;font-size:.78rem;letter-spacing:.05em; background:#fff;border:1px solid #cfe3d0;border-radius:10px;padding:12px 18px;color:var(--teal);} \/* CTA *\/ .vf-sci .cta{background:var(--teal);border-radius:22px;padding:56px 40px;text-align:center;margin-top:6px;} .vf-sci .cta h2{color:#fff;} .vf-sci .cta p{color:#cfe8e6;max-width:52ch;margin:0 auto 26px;} .vf-sci .btn{display:inline-block;background:var(--lime);color:var(--teal)!important;border-radius:10px; padding:15px 34px;font-weight:600;text-decoration:none;font-size:1.02rem;} .vf-sci .btn:hover{background:#fff;} \/* REFS *\/ .vf-sci .refs{background:var(--offwhite);border-top:1px solid #dcebe4;padding:44px 0;} .vf-sci .refs h3{font-size:1rem;font-family:'JetBrains Mono',monospace;text-transform:uppercase; letter-spacing:.1em;color:var(--green);margin-bottom:16px;} .vf-sci .refs ol{margin-left:20px;} .vf-sci .refs li{font-size:.9rem;color:#5c726f;margin-bottom:9px;line-height:1.5;} .vf-sci .disc{max-width:70ch;margin:26px auto 0;font-size:.8rem;font-style:italic;color:#7c8f8d;text-align:center;} @media(max-width:820px){ .vf-sci .trio,.vf-sci .duo,.vf-sci .cmp,.vf-sci .pillars{grid-template-columns:1fr;} .vf-sci .flow{grid-template-columns:1fr;} .vf-sci .arr{transform:rotate(90deg);} .vf-sci h1{font-size:2.4rem;} .vf-sci h2{font-size:1.6rem;} .vf-sci .sc .num{font-size:2.8rem;} } \/* theme-proof: fuerza blanco sobre fondos teal + badges en 1 l\u00ednea *\/ .vf-sci .cta h2,.vf-sci .measure h2,.vf-sci .card.dark h3{color:#fff!important;} .vf-sci .cta p,.vf-sci .measure p,.vf-sci .card.dark p{color:#cfe8e6!important;} .vf-sci .card.dark .tag,.vf-sci .step.hl .n{color:var(--mint)!important;} .vf-sci .step.hl .big,.vf-sci .step.hl small{color:#fff!important;} .vf-sci .badge{white-space:nowrap!important;} .vf-sci .ghost-cta{display:inline-block;margin-top:20px;font-family:'Inter Tight',sans-serif;font-size:.95rem;font-weight:600;color:#fff!important;text-decoration:none;border:1.5px solid rgba(157,224,222,.55);border-radius:8px;padding:11px 22px;} .vf-sci .ghost-cta:hover{border-color:var(--lime);color:var(--lime)!important;}\n<\/style>\n<div class=\"vf-sci\"><!-- HERO --><\/p>\n<header class=\"hero\">\n<div class=\"wrap\">\n<div class=\"eyebrow\">The Science<\/div>\n<h1>Resolve, don&#8217;t just reduce<\/h1>\n<p class=\"lead\">Most people think of omega-3 as a way to &#8220;calm&#8221; inflammation. The biology is more interesting: your body has an active, built-in program to <em>resolve<\/em> it &mdash; and omega-3 is the raw material it runs on.<\/p>\n<div class=\"kwords\"><span class=\"kw\">OMEGA-3 = SUBSTRATE<\/span><span class=\"kw\">SPMs = SIGNAL<\/span><span class=\"kw\">MEASURABLE<\/span><\/div>\n<\/div>\n<\/header>\n<p><!-- 1 \u00b7 EPIDEMIOLOGY --><\/p>\n<section>\n<div class=\"wrap center\"><span class=\"stepnum\">01 \u00b7 The problem<\/span><\/p>\n<h2>It&#8217;s more widespread than you&#8217;d think<\/h2>\n<p class=\"lead\">Three numbers that describe modern health &mdash; and they point in the same direction.<\/p>\n<div class=\"trio\">\n<div class=\"sc\">\n<div class=\"num\">15:1<\/div>\n<div class=\"lbl\">Omega-6 : Omega-3<\/div>\n<p>The typical fatty-acid ratio in the modern Western diet &mdash; when human physiology evolved closer to 1:1.<sup>1<\/sup><\/p>\n<\/div>\n<div class=\"sc\">\n<div class=\"num\">4.1%<\/div>\n<div class=\"lbl\">Omega-3 Index<\/div>\n<p>The average in U.S. adults, with more than half below 4%. A range linked to well-being sits closer to 8%.<sup>2<\/sup><\/p>\n<\/div>\n<div class=\"sc\">\n<div class=\"num\">1 in 8<\/div>\n<div class=\"lbl\">Metabolic health<\/div>\n<p>Only about 1 in 8 U.S. adults is in optimal metabolic health &mdash; low-grade inflammation runs underneath much of the rest.<sup>3<\/sup><\/p>\n<\/div>\n<\/div>\n<p class=\"tie\">Too much omega-6, too little omega-3, and a slow-burning inflammation that never fully switches off. That&#8217;s the backdrop.<\/p>\n<\/div>\n<\/section>\n<p><!-- 2 \u00b7 PARADIGM SHIFT --><\/p>\n<section style=\"background:#f4faf7;\">\n<div class=\"wrap\">\n<div class=\"center\"><span class=\"stepnum\">02 \u00b7 The shift<\/span><\/p>\n<h2>A different way to think about inflammation<\/h2>\n<p class=\"lead\">What if the goal isn&#8217;t to suppress the response, but to help the body <em>finish<\/em> it?<\/p>\n<\/div>\n<div class=\"cmp\">\n<div class=\"col a\">\n<h3>Reduction<\/h3>\n<ul>\n<li>Turns the signal <strong>down<\/strong><\/li>\n<li>Focuses on dampening the response<\/li>\n<li>Works like a brake &mdash; pressed from the outside<\/li>\n<li>Doesn&#8217;t, by itself, clear or repair<\/li>\n<\/ul>\n<\/div>\n<div class=\"col b\">\n<h3>Resolution<\/h3>\n<ul>\n<li>Actively <strong>switches the response off<\/strong><\/li>\n<li>A programmed, built-in process<\/li>\n<li>Clears debris and supports tissue repair<\/li>\n<li>Runs on omega-3-derived signals<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"center\" style=\"margin-top:56px;\">\n<h3 style=\"font-size:1.5rem;\">Two molecules, two jobs<\/h3>\n<p class=\"lead\" style=\"margin-top:8px;\">Resolution is a substrate and a signal working together.<\/p>\n<\/div>\n<div class=\"duo\">\n<div class=\"card\">\n<div class=\"tag\">The substrate<\/div>\n<h3>EPA &amp; DHA<\/h3>\n<p>The two long-chain omega-3 fatty acids from fish oil. They&#8217;re the raw material your body draws on to make its own resolution signals. Without enough substrate on board, the process simply has less to work with.<\/p>\n<\/div>\n<div class=\"card dark\">\n<div class=\"tag\">The signal<\/div>\n<h3>SPMs<\/h3>\n<p>Specialized Pro-resolving Mediators &mdash; resolvins, protectins and maresins. The molecules your body builds <em>from<\/em> EPA and DHA to actively bring the inflammatory response to a close and support tissue repair.<\/p>\n<\/div>\n<\/div>\n<div class=\"center\" style=\"margin-top:52px;\">\n<div class=\"step-tag\">The pathway<\/div>\n<\/div>\n<div class=\"flow\">\n<div class=\"step\">\n<div class=\"n\">You take<\/div>\n<div class=\"big\">EPA + DHA<\/div>\n<p><small>High-potency omega-3 as substrate<\/small><\/div>\n<div class=\"arr\">&rarr;<\/div>\n<div class=\"step hl\">\n<div class=\"n\">You build<\/div>\n<div class=\"big\">SPMs<\/div>\n<p><small>Resolvins \u00b7 Protectins \u00b7 Maresins<\/small><\/div>\n<div class=\"arr\">&rarr;<\/div>\n<div class=\"step\">\n<div class=\"n\">Your body<\/div>\n<div class=\"big\">Resolves<\/div>\n<p><small>Active clearing &amp; return to balance<\/small><\/div>\n<\/div>\n<p class=\"tie\">This is the mechanism first mapped by Prof. Charles Serhan&#8217;s lab at Harvard: inflammation doesn&#8217;t just fade &mdash; it&#8217;s actively switched off by pro-resolving mediators made from omega-3.<sup>4<\/sup><\/p>\n<\/div>\n<\/section>\n<p><!-- 3 \u00b7 MEASURE --><\/p>\n<section>\n<div class=\"wrap\">\n<div class=\"center\"><span class=\"stepnum\">03 \u00b7 You can measure it<\/span><\/p>\n<h2>This isn&#8217;t faith. It&#8217;s a number.<\/h2>\n<p class=\"lead\" style=\"margin:0 auto;\">Unlike most of what you take, your omega-3 status can be measured objectively &mdash; the <strong>Omega-3 Index<\/strong>: the percentage of EPA + DHA in your red blood cell membranes.<sup>5<\/sup><\/p>\n<\/div>\n<div class=\"measure\">\n<h2>Know your starting point &mdash; then watch it move<\/h2>\n<div class=\"gauge\"><span style=\"height:26%\"><\/span><span style=\"height:34%\"><\/span><span class=\"on\" style=\"height:42%\"><\/span><span style=\"height:56%\"><\/span><span style=\"height:70%\"><\/span><span class=\"on\" style=\"height:88%\"><\/span><\/div>\n<div class=\"glabel\">LOW &lt;4%&nbsp;&nbsp;\u00b7&nbsp;&nbsp;DESIRABLE 8%&nbsp;&nbsp;\u00b7&nbsp;&nbsp;OPTIMAL 10&ndash;12%<\/div>\n<p style=\"margin-top:22px;\">You don&#8217;t have to take it on trust. Under 4% is low, and 8% is the widely cited &#8220;desirable&#8221; mark &mdash; but for your body to really run like a rocket, you&#8217;re aiming for <strong style=\"color:#fff;\">10&ndash;12%<\/strong>. Measure where you start, give it real substrate, and watch the number climb.<\/p>\n<p style=\"margin-top:16px;font-size:.98rem;\">It&#8217;s measured with a simple finger-prick blood test &mdash; a few drops, at home.<\/p>\n<p><a class=\"ghost-cta\" href=\"\/us\/contact\/\">Interested in measuring yours? Get in touch &rarr;<\/a><\/div>\n<\/div>\n<\/section>\n<p><!-- 4 \u00b7 SOLUTION --><\/p>\n<section style=\"background:#f4faf7;\">\n<div class=\"wrap\">\n<div class=\"center\"><span class=\"stepnum\">04 \u00b7 What to actually do<\/span><\/p>\n<h2>A serious omega-3 &mdash; and SPMs<\/h2>\n<p class=\"lead\">Not all fish oil is the same &mdash; and real resolution takes more than fish oil. Three things set ours apart.<\/p>\n<\/div>\n<div class=\"pillars\">\n<div class=\"pillar\">\n<div class=\"ic\">Potency<\/div>\n<div class=\"val\">80%+<\/div>\n<p>combined EPA + DHA concentration in a re-esterified triglyceride form your body absorbs efficiently &mdash; not a diluted 30% oil.<\/p>\n<\/div>\n<div class=\"pillar\">\n<div class=\"ic\">Technology<\/div>\n<div class=\"val\">LIPINOVA&reg;<\/div>\n<p>built on LIPINOVA&reg;, a patented pro-resolution technology that is standardized to measured SPM precursors &mdash; what sets our pro-resolution range apart.<\/p>\n<\/div>\n<div class=\"pillar\">\n<div class=\"ic\">Freshness<\/div>\n<div class=\"val\">Low TOTOX<\/div>\n<p>total oxidation kept below the GOED Voluntary Monograph limit, with enteric protection so the oil stays intact until it&#8217;s absorbed.<sup>6<\/sup><\/p>\n<\/div>\n<\/div>\n<div class=\"spm-note\">\n<p><strong>And for the signal itself:<\/strong> a high-potency omega-3 gives your body the substrate. Our <strong>SPMs, built on LIPINOVA&reg;,<\/strong> deliver the measured precursors your body converts into them &mdash; 18-HEPE, 17-HDHA and 14-HDHA. Substrate and signal, working together.<\/p>\n<\/div>\n<div class=\"badges\"><span class=\"badge\">Patented LIPINOVA&reg;<\/span><span class=\"badge\">Third-Party Tested<\/span><span class=\"badge\">GOED Monograph<\/span><span class=\"badge\">Pharmaceutical standards<\/span><span class=\"badge\">IFOS Certified<\/span><\/div>\n<\/div>\n<\/section>\n<p><!-- CTA --><\/p>\n<section>\n<div class=\"wrap\">\n<div class=\"cta\">\n<h2>The substrate your body actually uses<\/h2>\n<p>High-potency, third-party-tested omega-3 and pro-resolution formulas &mdash; built on the science, not the slogan.<\/p>\n<p><a class=\"btn\" href=\"\/us\/shop\/\">Shop the range<\/a><\/div>\n<\/div>\n<\/section>\n<p><!-- REFERENCES --><\/p>\n<div class=\"refs\">\n<div class=\"wrap\">\n<h3>References<\/h3>\n<ol>\n<li>Simopoulos AP. <em>The importance of the ratio of omega-6\/omega-3 essential fatty acids.<\/em> Biomed Pharmacother. 2002;56(8):365&ndash;379.<\/li>\n<li>Powers KM, et al. <em>Omega-3 Index status in U.S. adults (NHANES 2021&ndash;2023).<\/em> Current Developments in Nutrition. 2026.<\/li>\n<li>Araujo J, Cai J, Stevens J. <em>Prevalence of Optimal Metabolic Health in American Adults: NHANES 2009&ndash;2016.<\/em> Metab Syndr Relat Disord. 2019;17(1):46&ndash;52.<\/li>\n<li>Serhan CN. <em>Pro-resolving lipid mediators are leads for resolution physiology.<\/em> Nature. 2014;510(7503):92&ndash;101.<\/li>\n<li>Harris WS, von Schacky C. <em>The Omega-3 Index: a new risk factor for death from coronary heart disease?<\/em> Prev Med. 2004;39(1):212&ndash;220.<\/li>\n<li>Global Organization for EPA and DHA Omega-3s (GOED). <em>Voluntary Monograph &mdash; oxidation (TOTOX) limits for omega-3 oils.<\/em><\/li>\n<\/ol>\n<p class=\"disc\">* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The Science Resolve, don&#8217;t just reduce Most people think of omega-3 as a way to &#8220;calm&#8221; inflammation. The biology is more interesting: your body has an active, built-in program to resolve it &mdash; and omega-3 is the raw material it runs on. OMEGA-3 = SUBSTRATESPMs = SIGNALMEASURABLE 01 \u00b7 The problem It&#8217;s more widespread than&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-blank.php","meta":{"_daextinma_seo_power":"","_daextinma_enable_ail":"","footnotes":""},"class_list":["post-51077","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/vibefarma.com\/us\/wp-json\/wp\/v2\/pages\/51077","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vibefarma.com\/us\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/vibefarma.com\/us\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/vibefarma.com\/us\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vibefarma.com\/us\/wp-json\/wp\/v2\/comments?post=51077"}],"version-history":[{"count":6,"href":"https:\/\/vibefarma.com\/us\/wp-json\/wp\/v2\/pages\/51077\/revisions"}],"predecessor-version":[{"id":51222,"href":"https:\/\/vibefarma.com\/us\/wp-json\/wp\/v2\/pages\/51077\/revisions\/51222"}],"wp:attachment":[{"href":"https:\/\/vibefarma.com\/us\/wp-json\/wp\/v2\/media?parent=51077"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}