{"id":50522,"date":"2026-08-14T12:51:09","date_gmt":"2026-08-14T11:51:09","guid":{"rendered":"https:\/\/vibefarma.com\/pt\/a-ciencia\/"},"modified":"2026-09-26T00:07:23","modified_gmt":"2026-09-25T23:07:23","slug":"ciencia","status":"publish","type":"page","link":"https:\/\/vibefarma.com\/pt\/ciencia\/","title":{"rendered":"A Ci\u00eancia"},"content":{"rendered":"<style>@import url('https:\/\/fonts.googleapis.com\/css2?family=Bricolage+Grotesque:opsz,wght@12..96,400..700&family=Inter+Tight:wght@400;500;600;700&family=JetBrains+Mono:wght@400;500&display=swap');\n.vf-sci{--teal:#004B53;--teal2:#00636d;--green:#258055;--lime:#D1FF80;--mint:#9DE0DE;--beige:#F4F2DC;--offwhite:#F8FDFF;--grey:#2A2A2A;--soft:#40625f;font-family:'Inter Tight',sans-serif;color:var(--grey);line-height:1.62;background:#fff}\n.vf-sci *{box-sizing:border-box;margin:0;padding:0}\n.vf-sci .wrap{max-width:1080px;margin:0 auto;padding:0 24px}\n.vf-sci .eyebrow,.vf-sci .step-tag{font-family:'JetBrains 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p{color:#cfe8e6!important;max-width:54ch;margin:0 auto 26px}\n.vf-sci .btn{display:inline-block;background:var(--lime);color:var(--teal)!important;border-radius:10px;padding:15px 34px;font-weight:600;text-decoration:none;font-size:1.02rem}\n.vf-sci .btn:hover{background:#fff}\n.vf-sci .refs{background:var(--offwhite);border-top:1px solid #dcebe4;padding:44px 0}\n.vf-sci .refs h3{font-size:1rem;font-family:'JetBrains Mono',monospace!important;text-transform:uppercase!important;letter-spacing:.1em!important;color:var(--green)!important;margin-bottom:16px}\n.vf-sci .refs ol{margin-left:20px}\n.vf-sci .refs li{font-size:.9rem;color:#5c726f;margin-bottom:9px;line-height:1.5}\n.vf-sci .disc{max-width:74ch;margin:26px auto 0;font-size:.8rem;font-style:italic;color:#7c8f8d;text-align:center}\n@media(max-width:820px){.vf-sci .trio,.vf-sci .duo,.vf-sci .cmp,.vf-sci .pillars,.vf-sci .flow{grid-template-columns:1fr}.vf-sci .arr{transform:rotate(90deg)}.vf-sci h1{font-size:2.4rem}.vf-sci h2{font-size:1.6rem}.vf-sci .sc .num{font-size:2.8rem}}\n<\/style>\n<div class=\"vf-sci\">\n<header class=\"hero\">\n<div class=\"wrap\">\n<div class=\"eyebrow\">A Ci\u00eancia<\/div>\n<h1>Resolver, n\u00e3o apenas reduzir<\/h1>\n<p class=\"lead\">Quase toda a gente pensa no \u00f3mega-3 como uma forma de \u00abacalmar\u00bb a inflama\u00e7\u00e3o. A biologia \u00e9 mais interessante: o corpo tem um programa pr\u00f3prio, ativo, para a <em>resolver<\/em> \u2014 e o \u00f3mega-3 \u00e9 a mat\u00e9ria-prima com que o faz.<\/p>\n<div class=\"kwords\"><span class=\"kw\">\u00d3MEGA-3 = SUBSTRATO<\/span><span class=\"kw\">SPM = SINAL<\/span><span class=\"kw\">MENSUR\u00c1VEL<\/span><\/div>\n<\/div>\n<\/header>\n<section>\n<div class=\"wrap center\"><span class=\"stepnum\">01 \u00b7 O problema<\/span><\/p>\n<h2>\u00c9 mais generalizado do que parece<\/h2>\n<p class=\"lead\">Tr\u00eas n\u00fameros que descrevem a sa\u00fade moderna \u2014 e apontam todos na mesma dire\u00e7\u00e3o.<\/p>\n<div class=\"trio\">\n<div class=\"sc\">\n<div class=\"num\">15:1<\/div>\n<div class=\"lbl\">\u00d3mega-6 : \u00d3mega-3<\/div>\n<p>o r\u00e1cio t\u00edpico de \u00e1cidos gordos na dieta ocidental \u2014 quando a fisiologia humana evoluiu perto de 1:1.<sup>1<\/sup><\/p>\n<\/div>\n<div class=\"sc\">\n<div class=\"num\">4,82%<\/div>\n<div class=\"lbl\">\u00cdndice de \u00d3mega-3 em Portugal<\/div>\n<p>a m\u00e9dia da popula\u00e7\u00e3o portuguesa, num estudo com 1.126 pessoas. S\u00f3 quem come peixe tr\u00eas ou mais vezes por semana se aproxima dos 6 %.<sup>2<\/sup><\/p>\n<\/div>\n<div class=\"sc\">\n<div class=\"num\">76%<\/div>\n<div class=\"lbl\">da popula\u00e7\u00e3o mundial<\/div>\n<p>n\u00e3o chega sequer aos 250 mg por dia de EPA + DHA \u2014 o m\u00ednimo recomendado pelas orienta\u00e7\u00f5es internacionais.<sup>3<\/sup><\/p>\n<\/div>\n<\/div>\n<p class=\"tie\">\u00d3mega-6 a mais, \u00f3mega-3 a menos, e uma inflama\u00e7\u00e3o de baixo grau que nunca se desliga por completo. \u00c9 este o pano de fundo.<\/p>\n<\/div>\n<\/section>\n<section style=\"background:#f4faf7\">\n<div class=\"wrap\">\n<div class=\"center\"><span class=\"stepnum\">02 \u00b7 A mudan\u00e7a<\/span><\/p>\n<h2>Outra forma de pensar a inflama\u00e7\u00e3o<\/h2>\n<p class=\"lead\">E se o objetivo n\u00e3o fosse suprimir a resposta, mas ajudar o corpo a <em>conclu\u00ed-la<\/em>?<\/p>\n<\/div>\n<div class=\"cmp\">\n<div class=\"col a\">\n<h3>Redu\u00e7\u00e3o<\/h3>\n<ul>\n<li>Baixa o <strong>volume<\/strong> do sinal<\/li>\n<li>Concentra-se em atenuar a resposta<\/li>\n<li>Funciona como um trav\u00e3o \u2014 premido de fora<\/li>\n<li>Por si s\u00f3, n\u00e3o limpa nem repara<\/li>\n<\/ul>\n<\/div>\n<div class=\"col b\">\n<h3>Resolu\u00e7\u00e3o<\/h3>\n<ul>\n<li><strong>Desliga ativamente<\/strong> a resposta<\/li>\n<li>\u00c9 um processo programado, pr\u00f3prio do corpo<\/li>\n<li>Remove restos e apoia a repara\u00e7\u00e3o dos tecidos<\/li>\n<li>Funciona com sinais derivados do \u00f3mega-3<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"center\" style=\"margin-top:56px\">\n<h3 style=\"font-size:1.5rem\">Duas mol\u00e9culas, dois pap\u00e9is<\/h3>\n<p class=\"lead\" style=\"margin-top:8px\">A resolu\u00e7\u00e3o \u00e9 um substrato e um sinal a trabalhar juntos.<\/p>\n<\/div>\n<div class=\"duo\">\n<div class=\"card\">\n<div class=\"tag\">O substrato<\/div>\n<h3>EPA e DHA<\/h3>\n<p>Os dois \u00e1cidos gordos \u00f3mega-3 de cadeia longa do \u00f3leo de peixe. S\u00e3o a mat\u00e9ria-prima de que o corpo parte para fabricar os seus pr\u00f3prios sinais de resolu\u00e7\u00e3o. Sem substrato suficiente, o processo tem menos com que trabalhar.<\/p>\n<\/div>\n<div class=\"card dark\">\n<div class=\"tag\">O sinal<\/div>\n<h3>SPM<\/h3>\n<p>Mediadores pr\u00f3-resolu\u00e7\u00e3o especializados \u2014 resolvinas, protectinas e maresinas. As mol\u00e9culas que o corpo constr\u00f3i <em>a partir<\/em> do EPA e do DHA para levar a resposta inflamat\u00f3ria ao seu fim e apoiar a repara\u00e7\u00e3o dos tecidos.<\/p>\n<\/div>\n<\/div>\n<div class=\"center\" style=\"margin-top:52px\">\n<div class=\"step-tag\">A via<\/div>\n<\/div>\n<div class=\"flow\">\n<div class=\"step\">\n<div class=\"n\">Voc\u00ea toma<\/div>\n<div class=\"big\">EPA + DHA<\/div>\n<p><small>\u00d3mega-3 de alta pot\u00eancia como substrato<\/small><\/div>\n<div class=\"arr\">\u2192<\/div>\n<div class=\"step hl\">\n<div class=\"n\">O corpo constr\u00f3i<\/div>\n<div class=\"big\">SPM<\/div>\n<p><small>Resolvinas \u00b7 Protectinas \u00b7 Maresinas<\/small><\/div>\n<div class=\"arr\">\u2192<\/div>\n<div class=\"step\">\n<div class=\"n\">E ent\u00e3o<\/div>\n<div class=\"big\">Resolve<\/div>\n<p><small>Limpeza ativa e regresso ao equil\u00edbrio<\/small><\/div>\n<\/div>\n<p class=\"tie\">Este \u00e9 o mecanismo descrito pela primeira vez pelo laborat\u00f3rio do Prof. Charles Serhan, em Harvard: a inflama\u00e7\u00e3o n\u00e3o se desvanece sozinha \u2014 \u00e9 desligada ativamente por mediadores pr\u00f3-resolu\u00e7\u00e3o fabricados a partir do \u00f3mega-3.<sup>4<\/sup><\/p>\n<\/div>\n<\/section>\n<section>\n<div class=\"wrap\">\n<div class=\"center\"><span class=\"stepnum\">03 \u00b7 E pode medir-se<\/span><\/p>\n<h2>Isto n\u00e3o \u00e9 uma quest\u00e3o de f\u00e9. \u00c9 um n\u00famero.<\/h2>\n<p class=\"lead\" style=\"margin:0 auto\">Ao contr\u00e1rio da maioria do que se toma, o estado de \u00f3mega-3 mede-se de forma objetiva \u2014 \u00e9 o <strong>\u00cdndice de \u00d3mega-3<\/strong>: a percentagem de EPA + DHA nas membranas dos gl\u00f3bulos vermelhos.<sup>5<\/sup><\/p>\n<\/div>\n<div class=\"measure\">\n<h2>Saiba de onde parte \u2014 e veja o n\u00famero mexer-se<\/h2>\n<div class=\"gauge\"><span style=\"height:26%\"><\/span><span style=\"height:34%\"><\/span><span class=\"on\" style=\"height:42%\"><\/span><span style=\"height:56%\"><\/span><span style=\"height:70%\"><\/span><span class=\"on\" style=\"height:88%\"><\/span><\/div>\n<div class=\"glabel\">MUITO BAIXO &lt;4 %&nbsp;&nbsp;\u00b7&nbsp;&nbsp;DESEJ\u00c1VEL 8 %&nbsp;&nbsp;\u00b7&nbsp;&nbsp;<span style=\"color:#D1FF80;font-weight:500\">O QUE PROCURAMOS 10\u201312 %<\/span><\/div>\n<p style=\"margin-top:22px\">Repare onde termina a escala: o intervalo-alvo publicado do \u00cdndice de \u00d3mega-3 vai dos <strong style=\"color:#fff\">8 aos 11 %<\/strong>.<sup>8<\/sup> Os 8 % s\u00e3o o piso do que \u00e9 bom, n\u00e3o a meta. Na Vibefarma apontamos aos <strong style=\"color:#fff\">10\u201312 %<\/strong>: a parte alta desse intervalo, e um ponto acima. \u00c9 um objetivo nosso, n\u00e3o um limiar oficial, e dizemo-lo assim. A m\u00e9dia portuguesa fica em <strong style=\"color:#fff\">4,82 %<\/strong>.<sup>2<\/sup> Me\u00e7a de onde parte, d\u00ea ao corpo substrato a s\u00e9rio, e veja o n\u00famero subir.<\/p>\n<p style=\"margin-top:16px;font-size:.98rem\">Mede-se com uma simples picada no dedo \u2014 umas gotas, em casa.<\/p>\n<p><a class=\"ghost-cta\" href=\"\/pt\/contacto\/\">Quer medir o seu? Fale connosco \u2192<\/a>\n<\/div>\n<\/div>\n<\/section>\n<section style=\"background:#f4faf7\">\n<div class=\"wrap\">\n<div class=\"center\"><span class=\"stepnum\">04 \u00b7 O que fazer na pr\u00e1tica<\/span><\/p>\n<h2>Um \u00f3mega-3 a s\u00e9rio \u2014 e os SPM<\/h2>\n<p class=\"lead\">Nem todos os \u00f3leos de peixe s\u00e3o iguais \u2014 e a resolu\u00e7\u00e3o exige mais do que \u00f3leo de peixe. Tr\u00eas coisas nos distinguem.<\/p>\n<\/div>\n<div class=\"pillars\">\n<div class=\"pillar\">\n<div class=\"ic\">Pot\u00eancia<\/div>\n<div class=\"val\">85%<\/div>\n<p>de concentra\u00e7\u00e3o de \u00f3mega-3 em forma de triglic\u00e9rido (TG), que o corpo absorve de modo eficiente \u2014 n\u00e3o um \u00f3leo dilu\u00eddo a 30 %.<\/p>\n<\/div>\n<div class=\"pillar\">\n<div class=\"ic\">Tecnologia<\/div>\n<div class=\"val\">LIPINOVA\u00ae<\/div>\n<p>constru\u00eddo com LIPINOVA\u00ae, uma tecnologia patenteada padronizada em precursores de SPM medidos e quantificados \u2014 \u00e9 o que distingue a nossa gama de pr\u00f3-resolu\u00e7\u00e3o. Num ensaio aleatorizado, duplo-cego e controlado por placebo, um \u00f3leo marinho enriquecido nestes precursores aumentou de forma mensur\u00e1vel a sua concentra\u00e7\u00e3o no sangue.<sup>7<\/sup><\/p>\n<\/div>\n<div class=\"pillar\">\n<div class=\"ic\">Frescura<\/div>\n<div class=\"val\">TOTOX baixo<\/div>\n<p>oxida\u00e7\u00e3o total mantida abaixo do limite da Monografia Volunt\u00e1ria GOED, com prote\u00e7\u00e3o ent\u00e9rica para que o \u00f3leo chegue intacto ao ponto de absor\u00e7\u00e3o.<sup>6<\/sup><\/p>\n<\/div>\n<\/div>\n<div class=\"spm-note\">\n<p><strong>E quanto ao sinal:<\/strong> um \u00f3mega-3 de alta pot\u00eancia d\u00e1 ao corpo o substrato. Os nossos <strong>SPM, constru\u00eddos com LIPINOVA\u00ae,<\/strong> entregam os precursores medidos que o organismo converte nos seus mediadores. Substrato e sinal, a trabalhar juntos.<\/p>\n<\/div>\n<div class=\"badges\"><span class=\"badge\">LIPINOVA\u00ae patenteado<\/span><span class=\"badge\">Analisado por terceiros<\/span><span class=\"badge\">Monografia GOED<\/span><span class=\"badge\">Padr\u00f5es farmac\u00eauticos<\/span><span class=\"badge\">Certificado IFOS&#x2122;<\/span><\/div>\n<\/div>\n<\/section>\n<section>\n<div class=\"wrap\">\n<div class=\"cta\">\n<h2>O substrato que o seu corpo realmente utiliza<\/h2>\n<p>\u00d3mega-3 de alta pot\u00eancia e f\u00f3rmulas de pr\u00f3-resolu\u00e7\u00e3o, analisados por terceiros \u2014 constru\u00eddos sobre a ci\u00eancia, n\u00e3o sobre o slogan.<\/p>\n<p><a class=\"btn\" href=\"\/pt\/loja\/\">Ver a loja<\/a><\/div>\n<\/div>\n<\/section>\n<div class=\"refs\">\n<div class=\"wrap\">\n<h3>Refer\u00eancias<\/h3>\n<ol>\n<li>Simopoulos AP. <em>The importance of the ratio of omega-6\/omega-3 essential fatty acids.<\/em> Biomed Pharmacother. 2002;56(8):365\u2013379.<\/li>\n<li>Cardoso C, Gomes R, Francisco J, Sapatinha M, Afonso C, Bandarra NM. <em>The omega-3 index: a study on the Portuguese population.<\/em> International Journal of Public Health Science. 14(2).<\/li>\n<li>Minihane AM, Cawood AL, Calder PC. <em>Omega-3 intakes and status worldwide.<\/em> Nutrition Research Reviews. 2025.<\/li>\n<li>Serhan CN. <em>Pro-resolving lipid mediators are leads for resolution physiology.<\/em> Nature. 2014;510(7503):92\u2013101.<\/li>\n<li>Harris WS, von Schacky C. <em>The Omega-3 Index: a new risk factor for death from coronary heart disease?<\/em> Prev Med. 2004;39(1):212\u2013220.<\/li>\n<li>Global Organization for EPA and DHA Omega-3s (GOED). <em>Voluntary Monograph \u2014 limites de oxida\u00e7\u00e3o (TOTOX) para \u00f3leos de \u00f3mega-3.<\/em><\/li>\n<li>Souza PR, Marques RM, Gomez EA, et al. <em>Enriched marine oil supplements increase peripheral blood specialized pro-resolving mediators concentrations and reprogram host immune responses: a randomized double-blind placebo-controlled study.<\/em> Circ Res. 2020;126(1):75\u201390.<\/li>\n<li>von Schacky C. <em>Omega-3 index in 2018\/19.<\/em> Proc Nutr Soc. 2020;79(4):1\u20137.<\/li>\n<\/ol>\n<p class=\"disc\">Esta p\u00e1gina descreve processos fisiol\u00f3gicos normais e tem finalidade informativa. N\u00e3o constitui aconselhamento m\u00e9dico. Os suplementos alimentares n\u00e3o substituem um regime alimentar variado e equilibrado nem um estilo de vida saud\u00e1vel, e n\u00e3o se destinam a diagnosticar, tratar, curar ou prevenir qualquer doen\u00e7a.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A Ci\u00eancia Resolver, n\u00e3o apenas reduzir Quase toda a gente pensa no \u00f3mega-3 como uma forma de \u00abacalmar\u00bb a inflama\u00e7\u00e3o. A biologia \u00e9 mais interessante: o corpo tem um programa pr\u00f3prio, ativo, para a resolver \u2014 e o \u00f3mega-3 \u00e9 a mat\u00e9ria-prima com que o faz. \u00d3MEGA-3 = SUBSTRATOSPM = SINALMENSUR\u00c1VEL 01 \u00b7 O problema&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-blank.php","meta":{"_daextinma_seo_power":"1000","_daextinma_enable_ail":"","footnotes":""},"class_list":["post-50522","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/vibefarma.com\/pt\/wp-json\/wp\/v2\/pages\/50522","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vibefarma.com\/pt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/vibefarma.com\/pt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/vibefarma.com\/pt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vibefarma.com\/pt\/wp-json\/wp\/v2\/comments?post=50522"}],"version-history":[{"count":7,"href":"https:\/\/vibefarma.com\/pt\/wp-json\/wp\/v2\/pages\/50522\/revisions"}],"predecessor-version":[{"id":50778,"href":"https:\/\/vibefarma.com\/pt\/wp-json\/wp\/v2\/pages\/50522\/revisions\/50778"}],"wp:attachment":[{"href":"https:\/\/vibefarma.com\/pt\/wp-json\/wp\/v2\/media?parent=50522"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}